Publications

The following publications by our students and faculty were made possible, in part, by the NMR Facility:

Wang, Q.; Deloia, M.A.; Kang, Y.; Litchke, C.; Zhang, N.; Titus, M.A.; Walters, K.J., Protein Science, 16, (2007) 189-196.

Kang, Y.; Zhang, N.; Koepp, D.M.; Walters, K.J.; "Ubiquitin Receptor Proteins hHR23a and hPLIC2 Interact", J. Mol. Biol., 365, (2007) 1093-1101.

Peterson, A.A.; McNeill, K.; "Catalytic Dehalogenation of sp2 C-F and C-Cl Bonds in Fluoro- and Chloroalkenes", Organometallics, 25(21), (2006) 4938-4940.

Liu, F.; Zhang, N.; Zhou, X.; Hanna, P.E.; Wagner, C.R.; Koepp, D.M.; Walters, K.J.; "Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation" J. Mol. Biol, 361, (2006) 482-492.

Fisher, A.; Mann, A.; Verma, V.; Thomas, N.; Mishra, R.K.; Johnson, R.L.; "Design and Synthesis of Photoaffinity-Labeling Ligands of the L-Prolyl-L-leucylglycinamide Binding Site Involved in the Allosteric Modulation of the Dopamine Receptor", J. Med Chem, 49, (2006) 307-317.

Hecht, S.S.; Huang, C.; Stoner, G.D.; Li, J.; Kenney, P.M.J.; Sturla, S.J.; Carmella, S.G., "Identification of Cyanidin Glycosides as Potential Chemopreventive Constituents of Freeze-Dried Black Raspberries", Carcinogenesis, (2006) in press.

Henry P-G, Marjanska M, Walls JD, Valette J, Gruetter R, Ugurbil K. POCE NMR Spectroscopy in Strongly Coupled Second Order Spin Systems. Magn Reson Med 2006; 55(2):250-257

Dinesh Kumar Deelchand, Kamil Ugurbil, Pierre-Gilles Henry, "Investigating Brain Metabolism at High Fields using Localized 13C NMR Spectroscopy wihtout 1H Decoupling", Magnetic Resonance in Medicine, 55, 279-286 (2006).

Traaseth, J.J., D.D. Thomas and G. Veglia. 2006. Effects of Ser16 phosphorylation on the allosteric transitions of phospholamban/Ca(2+)-ATPase complex. J. Mol. Biol. 358: 1041-50.

Buffy, J.J., B.A. Buck-Koehntop, F. Porcelli, N.J. Traaseth, D.D. Thomas and G. Veglia. 2006. Defining the intramembrane binding mechanism of sarcolipin to calcium ATPase using solution NMR spectroscopy. J Mol Biol, 358: 420-9.

Kang, Y., Vossler, R.A., Diaz-Martinex, L.A., Winter, N.S., Clarke, D.J., Walters, K.J.; "UBL/UBA Ubiquitin Receptor Proteins Bind a Common Tetraubiquitin Chain", (2006) J. Mol. Biol., 356,1027-1035.

Gong, J.; Neels, J.F.; Yu, X.; Kensler, T.W.; Peterson, L.A.; Sturla, S.J., "Investigating the Role of Stereochemistry in the Activity of Anticancer Acylfulvenes: Synthesis, Reductase-Mediated Bioactivation and Cellular Toxicity, J Med Chem, 49, 2593-2599 (2006).

Nguyen, T.N.T.; Bertagnolli, A.D.; Villalta, P.W.; Buhlmann, P.; Sturla, S.; "Characterization of a deoxyguanosine adduct of tetrachlorobenzoquinone: Dichlorobenzoquinone-1, N2-etheno-2'-deoxyguanosine", J. Chem. Res. Toxicol. 18, 1770-1776.

Sorensen, P.W.; Fine, J.M.; Dvornikovs, V.; Jeffrey, C.S.; Shao F.; Wang, J.; Vrieze, L.A.; Anderson, K.R.; Hoye, T.R. "Mixture of new sulfated steroids functions as a migratory pheromone in the sea lamprey", (2005) Nature Chem. Biol., 1(6), 324-328.

Buck-Koehntop, B.A., A. Mascioni, et al. (2005). "Structure, dynamics, and membrane topology of stannin: a mediator of neuronal cell apoptosis induced by trimethyltin chloride." J Mol Biol 354(3):652-65.

Wang, Q., Young, P., Walters, K.J., "Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition", (2005) J.Mol. Biol., 348, 727-739. Cover

Gronwald, J.W., Plaisance, K.L., Marimanikkuppam, S., Ostrowski, B.G., "Tagetitoxin Purification and Partial Characterization", (2005) Physiological and Molecular Plant Pathology, 67, 23-32.

Somu, R.V., Johnson, R.L., "Synthesis of Pipecolic Acid-Based Spiro Bicyclic Lactam Scaffolds as b-Turn Mimics", (2005) Journal of Organic Chemistry, 70,5954-63.

Sturla, S. J., Scott, J., Lao, Y., Hecht, S.S., Vilalta, P.W., "Mass Spectrometric Analysis of Relative Levels of Pyridyloxobutylation Adducts Formed in the Reaction of DNA with a Chemically Activated Form of the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)", (2005) Chem. Res. Toxicol., in press.

Devany, M.; Matsuo, H., "NMR Resonance assignments for the DNA-supercoiling domain of the human protein DEK" [Letter] (2005), Journal of Biomolecular NMR, 31(1), 65.

Devany, M.; Kotharu, N.P.; Matsuo, H.; "Expression and isotopic labeling of structural domains of the human protein DEK", (2005) Protein Expression and Purification, 40, 244-247.

Metcalfe, E.E.; Traaseth, N.J.; Veglia, G.; "Serine 16 Phosphorylation Induced an Order-to-Disorder Transition in Monomeric Phospholamban", (2005) Biochemistry, 44, 4386-4396.

Zamoon, J., Nitu, F., Karim, C., Thomas, D.D., Veglia, G., "Mapping the interaction surface of a membrane protein: Unveiling the conformational switch of phospholamban in calcium pump regulation", (2005) PNAS, 102, 4747-4752.

Metcalfe, E.E., Traaseth, N.J., Veglia, G., "Serine 16 Phosphorylation Induces an Order-to-Disorder Transition in Monomeric Phospholamban", (2005) Biochemistry, 44, 4386-4396.

Orsini, MJ, Nesmelova, I., Young, H.C., Hargittai, B., Beavers, M.P., Liu, J., Connolly, P.J., Middleton, S.A., Mayo, K.H., "The Nociceptin Pharmacophore Site for Opioid Receptor Binding Derived from the NMR Structure and Bioactivity Relationships" (2005) Journal of Biological Chemistry, 280, 8134-8142.

Nesmelova, I.V., Sham, Y., Dudek, A.Z., van Eijk, L.I., Wu, G., Slungaard, A., Mortari, F., Griffioen, A.W., Mayo, K.H., "Platelet Factor 4 and Interleukin-8 CXC Chemokine Heterodimer Formation Modulates Function at the Quaternary Structural Level", (2005) Journal of Biological Chemistry, 280, 4948-4958.

Hummel MA, Gannett PM, Aguilar JS, Tracy TS. "Effect-Mediated Alteration of Substrate Orientation in Cytochrome P450 2C9." Biochemistry, 43, 7207-7214.

Wang, Q., Walters, K.J., "Chemical Shift assignments of the (poly)ubiquitin-binding region of the proteasome subunit S5a", (2004) J.Biomol.NMR, 30, 231-232.

Oz, G.; Berkich, D.A.; Henry, P.G.; Xu, Y.; LaNoue, K.; Hutson, S.M.; Gruetter, R.; "Neuroglial metabolism in the awake rate brain: CO2 fixation increases with brain activity", J. Neurosci., 24, 11273-11279.

Porcelli, F., Buck, B., L, D.-K, Hallock, K.J., Ramamoorthy, A., Veglia, G., "Structure and Orientation of Pardaxin Determined by NMR Experiments in Model Membranes", (2004) Journal of Biological Chemistry, 279, 45815-45823.

Idiyatullin, D., Daragan, V.A., Mayo, K.H., "A simple method to measure 13CH2 heteronuclear dipolar cross-correlation spectral densities", (2004) Journal of Magnetic Resonance, 171, 4-9.

Nesmelova, I.V., Idiyatullin, D., Mayo, K.H., "Measuring protein self-diffusion in protein-protein mixtures using a pulsed gradient spin-echo technique with WATERGATE and isotope filtering", (2004) Journal of Magnetic Resonance, 166, 129-33.

Lockwood, N.A., Haseman, J.R., Tirrell, M.V., Mayo, K.H., "Acylation of SC4 dodecapeptide increases bacterial potency against Gram-positive bacteria, including drug-resistant strains", (2004) Biochem. J., 378, 93-103.

Tulla-Puch, J., Getun, I.V., Woodward, C., Barany, G., "Native-like conformations are sampled by partially folded and disordered variants of bovine pancreatic trypsin inhibitor", (2004) Biochemistry, 43, 1591-8.

Balcome, S., Park, S., Quirk Dorr, D.R., Hafner, L., Phillips, L., Tretyakova, N., "Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards", (2004)Chemical Research in Toxicology, 17, 950-62.

Park, S., Tretyakova, N., "Structural characterization of the major DNA-DNA crosslink of 1,2,3,4-diepoxybutane", (2004) Chemical Research in Toxicology, 31, 1984-94.

Cobine, P.A.; McKay, R.T.; Zangger, K.; Dameron, C.T.; Armitage, I.M.; "Solution structure of Cu6 metallothionein from the fungus Neurospora crassa", (2004) Eur. J. Biochem, 271, 4213-4221.

Xu, Y.; Oz, G.; LaNoue, K.F.; Keiger, C.J.; Gruetter, R.; Hutson, S.H.; "Whole-brain glutamate metabolism evaluated by steady-state kinetics using a double-isotope procedure: effects of gabapentin", (2004) J Neurochem, 90(5), 1104-16.

Devany, M.; Kotharu, N.P.; Matsuo, H.; "Solution NMR structure of the C-terminal domain of the human protein DEK", (2004) Protein Science, 13, 2252-2259.

Metcalfe, E.E.; Zamoon, J.; Thomas, D.D.; Veglia, G.; "1H/15N Heteronuclear NMR Spectroscopy Shows Four Dynamic Domains for Phospholamban Reconstituted in Dodecylphosphocholine Micelles.", (2004) Biophys. J, 87:1205-1214.

Buck, B.A., Mascioni, A., Cramer, C.J., Veglia, G.; "Interactions of Alkyltin Salts with Biological Dithiols: Dealkylation and Induction of a Regular Beta-Turn Structure in Peptides", (2004) JACS, 126, 14400-14410.

Henry, P.-G.; Oz, Gulin; Provencher, S.; Gruetter, R.; "Toward dynamic isotopomer analysis in the rat brain in vivo: automatic quantitation of 13C NMR spectra using LCModel", (2003) NMR in Biomedicine, 16, 400-412.

Zamoon, J.; Mascioni, A.; Thomas, D.D.; Veglia, G.; "NMR Solution structure and topological orientation of monomeric phospholamban in dodecylphosphocholine micelles", (2003) Biophys J., 85, 2589-2598.

Buck, B.; Zamoon, J.; Kirby, T.L.; DeSilva, T.M.; Karim, C.B.; Thomas, D.D.; Veglia, G.; "Overexpression, purification and characterization of recombinant Ca-ATPase regulators for high-resolution solution and solid-state NMR studies.", (2003) Protein Expr. Purif., 30, 253-261.

Wang, Q.; Goh, A.M.; Howley, P.M.; Walters, K.J.; "Ubiquitin Recognition by the DNA Repair Protein hHR23a", (2003) Biochemistry, 42, 13529-13535.

Walters, K.J.; Lech, P.J.; Goh, A.M.; Wang, Q.; Howley, P.M.; "DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a", (2003) PNAS, 100, 12694-12699.

Dings, R.P.M.; Arroyo, M.; van Eijk, L.; Grieffioen, A.W.; Mayo, K.H.; "ß-Sheet is the Bioactive Conformation of the Anti-Angiogenic Peptide Anginex", (2003) Biochem. J., in press

Dudek, A.Z.; Nesmelova, I.; Mayo, K.H.; Verfaillie, C.M.; Pitchford, E.; Slungaard, A.; "Platelet Factor 4 Promotes Adhesion of Hematopoietic Progenitor Cells and Binds IL-8: Novel Mechanisms for Modulation of Hematopoiesis", (2003) Blood, (in press).

Dings, R.P.M.; Grieffioen, A.; Mayo, K.H.; "Discovery and Development of Antiangiogenic Peptides: a Structural Link", (2003) Angiogenesis, in press.

Idiyatullin, D.; Daragan, V.A.; Mayo, K.H.; "¹⁵NH Bacbone Dynamics of Protein GB1: Comparison of Order Parameters and Correlation Times Derived using Various 'Model Free' Approaches"; (2003) J. Phys. Chem., 107, 2602-2609. .

Grieffioen, A.; Mayo, K.H.; "Designing ßpep Peptides: A Rational Approach to Discovery of Novel Pharmaceutical Agents and Small Molecules", (2003), Drugs of the Future, in press.

Idiyatullin, D.; Nesmelova, I.; Daragan, V.A.; Mayo, K.H.; "Comparison of ¹³Calpha H ¹⁵NH Backbone Dynamics in Protein GB1", (2003) Protein Science, 12, 912-922.

Dings, R.P.M.; Hargittai, B.; Haseman, J.; Grieffioen, A.W.; Mayo, K.H.; "Anti-tumor activity of the novel angiogenesis inhibitor anginex", (2003) Cancer Letters, 194, 55-66.

Idiyatullin, D.; Daragan, V.A.; Mayo, K.H.; "Protein Dynamics using Frequency-Dependent Order Parameters from Analysis of NMR Relaxation Data", (2003) J. Magn. Reson., 161, 118-125.

Dings, R.P.M.; Yokoyama, Y.; Ramakrishnan, S.; Griffioen, A.W.; Mayo, K.H.; "The designed angiostatic peptide anginex synergistically improves chemotherapy and anti-angiogenesis therapy with angiostatin", (2003) Cancer Res., 63, 382-385.

Idiyatullin, D.; Nesmelova, I.; Daragan, V.A.; Mayo, K.H.; "Heat Capacities and a Snapshot of the Energy Landscape in Protein GB1 from the Pre-Denaturation Temperature Dependence of Backbone NH Nanosecond Fluctuations", (2003) J.Mol.Biol., 325, 149-162.

Lockwood, N.; van Tankeren, R.; McKernan, S.; Mayo, K.H.; "Aqueous Gel Derived from the ß-Sheet Domain of Platelet Factor-4", (2002) Biomacromolecules, 3, 1225-1232.

van der Schaft, Dings, R.P.M.; de Lussanet, Q.R.; van Eijk, L.I.; Nap, A.W.; Beets-Tan, R.G.H.; Bouma-Ter Steege, J.C.A.; Wagstaff, J.; Mayo, K.H.; Griffioen, A.W.; "The Designer Antiangiogenic Peptide Anginex Targets Tumor Endothelial Cells and Inhibits Tumor Growth in Animal Models", (2002) FASEB Journal, 16, 1991-1993.

van der Schaft, D.W.J.; Wagstaff, J.; Mayo, K.H.; Griffioen, A.W.; "The Antiangiogeneic Properties of Bactericidal/Permeability Increasing Protein (BPI)", (2002) Annals of Medicine, 34, 19-27.

Coltart, D.M.; Royyuru, A.K.; Williams, L.J.; Glunz, P.W.; Sames, D.; Kuduk, S.D.; Schwarz, J.B.; Chen, X.-T.; Danishefsky, S.J.; Live, D.H.; "Principles of Mucin Architecture: Structural Stuies on Synthetic Glycopeptides Bearing Clustered Mono-, Di-, Tri-, and Hexassaccharide Glycodomains", (2002) Journal of the American Chemical Society, 124, 9833-9844.

Barbeau, K.; Zhang, G.; Live, D.H.; Butler, A.; "Petrobactin, a Photoreactive Siderophore Produced by the Oil-Degrading Marine Bacterium Marinobacter hydrocarbonoclasticus", (2002) Journal of the American Chemical Society, 124, 378-379.

Kallick, D.A.; Nagan, M.C.; Beuning, P.J.; Kerimo, S.; Tessmer, M.R.; Cramer, C.J.; Musier-Forsyth, K.; "Discrimination of C1:G72 microhelixAla by AlaRS is based on specific atomic groups rather than conformational effects: An NMR and MD analysis", (2002) Journal of Physical Chemistry B, 106, 8878-8884 .

Battiste, J.L.; Li, R.; Woodward, C.; "A Highly Destablizing Mutation, G37A, of the Bovine Pancreatic Trypsin Inhibitor Retains the Average Native Conformation but Greatly Increases Local Flexibility", (2002) Biochemistry, 41, 2237-2245.

Li, R.; Battiste, J.L.; Woodward, C.; "Native-like Interactions Favored in the Unfolded Bovine Pancreatic Trypsin Inhibitor Have Different Roles in Folding", (2002) Biochemistry, 41, 2246-2253.

Wu, M.; Simpson, C.D.; Christiani, D.C.; Hecht, S.S.; "Relationship of exposure to coke-oven emission and urinary metabolites of benzo[a]pyrene and pyrene in coke-oven workers", (2002) Cancer Epidemiol. Biomarkers & Prev., 11, 311-314.

Mascioni, A.; Karim, C.; Barany, G.; Thomas, D.D.; Veglia, G.; "Structure and Orientation of Sarcolipin in Lipid Environments", (2002) Biochemistry, 41, 475-482.

Wang, M.; McIntee, E.J.; Cheng, G.; Shi, X.; Villalta, P.W.; Hecht, S.S.; "A Schiff base is a major DNA adduct of crotonaldehyde", (2001) Chem. Res. Toxicol., 14, 423-430.

Upadhyaya, P.; McIntee, E.J.; Hecht, S.S.; "Preparation of pyridine-N-glucuronides of tabacco-specific nitrosamines", (2001) Chem. Res. Toxicol., 14, 555-561.

Wang, M.; McIntee, E.J.; Cheng, G.; Shi, Y.E.; Villalta, P.W.; Hecht, S.S.; "Reactions of 2,6-dimethyl-1,3-dioxane-4-ol (aldoxane) with deoxyguanosine and DNA", (2001) Chem. Res. Toxicol., 14, 1025-1032.

Wiedmann, T.S.; Herrington, H.; Deye, C.; Kallick, D.; "Interaction of sodium taurocholate and egg phosphatidylcholine aggregates in rat intestinal mucin", (2001) Pharm. Res., 18, 1489-1496.

Wiedmann, T.S.; Herrington, H.; Deye, C.; Kallick, D.; "Analysis of the diffusion of bile salt/phospholipid micelles in mucin", (2001) Chem. Phys. Lipids, 112, 81-92.

Barbar, E.; Hare, M.; Makokha, M.; Barany, G.; Woodward, C.; "NMR-Detected Order in Core Residues of Denatured Bovine Pancreatic Trypsin Inhibitor", (2001) Biochemistry, 40, 9734-9742.

Oz, G.; Zangger, K.; Armitage, I.; "Three-dimensional Structure and Dynamics of a Brain specific Growth Inhibitory Factor: Metallothionein-3", (2001) Biochemistry, 40, 11433-11441.

Bozzi, M.; Veglia, G.; Paci, M.; Sciandra, F.; Giardina, B.; Brancaccio, A.; "A synthetic peptide corresponding to the 550-585 region of alpha-dystroglycan binds beta-dystroglycan as revealed by NMR spectroscopy", (2001) FEBS Letters, 24979, 1-5.

Idiyatullin, D.; Daragan, V.A.; Mayo, K.H.; "A New Approach to Visualizing Spectral Density Functions and Deriving Motional Correlation Time Distributions: Applications to an alpha-Helix-Forming peptide and to a Well-Folded Protein", (2001) Journal of Magnetic Resonance, 152, 132-148.

Cox, A.; Arroyo, M.; Mayo, K.H.; "Effects on Folding and Self-Association from Substitution of Hydrophobic Residues at the Beta-Sheet Sandwich Interface of Bpep-4", (2001) Biochem.J., 357, 739-747.

Chang, S.L.; Wallar, B.J.; Lipscomb, J.D.; Mayo, K.H.; "Residues in Methylosinus trichosporium OB3b Methane Monoxygenase Component B Involved in Molecular Interactions with Reduced- and Oxidized-Hydroxylase Component: a Role for the N-Terminus", (2001) Biochemistry, 40(32), 9539-9551.

Idiyatullin, D.; Daragan, V.A.; Mayo, K.H.; "Improved Measurement of 15N-{1H} NOEs in the Presence of NH-Water Proton Chemical Exchange", (2001) J. Magn. Reson., 153, 138-143.

Zangger, K.; Armitage, I.M.; "Dynamics of Interdomain Interactions in Mammalian Metallothioneins", (2001) J.Inorg. Biochem., 88, 135-143.

Zangger, K.; Shen, G.; Oz, G.; Otvos, J.D.; Armitage, I.M.; "Oxidative Dimerization in Metallothionein is a Result of Intermolecular Disulfide Bonds between Cysteines in the alpha-Domain", (2001) Biochem. J., 359, 353-360.

Wiedmann, T.S.; Deye, C.; Kallick, D.; "Interaction of bile salt and phospholipids with bovine submaxillary mucin", (2001) Pharmaceutical Research, 18, 45-53.

Nesmelova, I.; Krusheknitsky, A.; Idiyatullin, D.; Blanco, F.; Ramirez-Alvarado, M.; Daragan, V.A.; Serrano, L.; Mayo, K.H.; "Conformational Exchange on the Microsecond Time Scale in alpha-Helix and Beta-Hairpin Peptides Measured by 13C-NMR Transverse Relaxation", (2001) Biochemistry, 40, 2844-2853.

Beavers, M.P.; Gunnet, J.W.; Hageman, W.; Miller, W.; Moore, J.B.; Zhou, L.; Chen, R.; Xiang, A.; Urbanski, M.; Combs, D.W.; Mayo, K.H.; Peterson, P.A.; Demarest, K.T.; "Discovery of the First Non-Peptide Antagonist of the Motilin Receptor", (2001) Drug Design & Discovery, 17, 243-251.

Griffioen, A.W.; van der Shaft, D.; Barandsz-Janson, A.; Cox, A.; Struijker-Boudier, H.A. Hillen, H.F.P.; Mayo, K.H.; "Anginex, a designed Peptide that Inhibits Angiogenesis", (2001) Biochem. J., 354, 233-242.

He, M.; Sheldon, P.J.; Sherman, D.H.; "Characterization of a quinone reductase activity for the mitomycin C binding protein (MRD): Functional switching from a drug-activating enzyme to a drug-binding protein", (2001) Proc. Natl. Acad. Sci., 98, 926-931.

Arlandson, M.; Decker, T.; Roongta, V.A.; Bonilla, L.; Mayo, K.H.; MacPherson, J.C.; Hazen, S.L.; Slungaard, A.; "Eosinophil Peroxidase Oxidation of Thiocyanate", (2001) Journal of Biological Chemistry, 276, 215-224.

Wang, M.; McIntee, E.J.; Cheng, G.; Shi Y.; Villalta, P.W.; Hecht, S.S.; "Identification of paraldol-deoxyguanosine adducts in DNA reacted with crotonaldehyde",(2000) Chem. Res. Toxicol., 13, 1065-1074.

Hecht, S.S.; Hochlater, J.B.; Villalta, P.W.; Hecht, S.S.; "2'-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: formation of a lung carcinogenic precursor", (2000) Proc. Natl. Sci., 97, 12493-12497.

Wang, M.; McIntee, E.J.; Cheng, G.; Shi, Y.; Villalta, P.; Hecht, S.S.; "Identification of DNA Adducts of Acetaldehyde", (2000) Chem. Res. Toxicol., 13, 1149-1157.

Okar, D.A.; Live, D.H.; Devany, M.H.; Lange, A.J.; "Mechanism of the Biphosphatase Reaction of 6-Phosphofructo-2-kinase/Fructose-2,6-Biphosphatase Probed by 1H-15N NMR Spectroscopy", (2000) Biochemistry, 39, 9654-9762.

Mayo, K.H., "Recent Advances in the Design and Construction of Synthetic Peptides: for the Love of Basics or just for the Technology of it", (2000) Trends in Biotechnology, 18, 212-217.

Daragan, V.A.; Voloshin, A.M.; Chochina, S.V.; Khazanovich, T.N.; Wood, W.G.; Avdulov, N.A.; Mayo, K.H.; "Specific Binding of Ethanol to Cholesterol", (2000) Biophysical J., 79, 406-415.

Mayo, K.H.; Haseman, J.; Young, H.C.; Mayo, J.W.; "Structure-Function Relations in Novel Peptide Dodecamers with Broad Spectrum Bactericidal and Endotoxin Neutralizing Activities", (2000) Biochem. J., 349, 717-728.

Van der Schaft, D.; Toebes, E.A.H.; Haseman, J.R.; Mayo, K.H.; Griffioen, A.W.; "Bactericidal/Permeability-Increasing Protein (B/PI) Inhibits Angiogenesis via Induction of Apoptosis in Vascuular Endothelial Cells", (2000) Blood, 96, 176-181.

Zangger, K.; Armitage, I.M.; "The Accordian-HMQC: Heteronuclear Correlations Over a Range of Coupling Constants", J. Magn. Reson., 38, 452-458.

Mayo, K.H.; Daragan, V.A., Idiyatullin, D.; Nesmelova, I.; "Peptide internal motions on nanosecond time scale from direct fitting of 13C- & 15N-NMR spectral density maps", (2000) J.Mag.Reson., 146, 188-195.

Idiyatullin, D.; Krusheknitsky, A.; Nesmelova, I.; Blanco, F.; Daragan, V.A.; Serrano, L.; Mayo, K.H.; "Internal motional amplitudes and correlated bond rotations in an alpha-helix peptide derived from 13C- and 15N-NMR relaxation", (2000) Protein Science, 9, 2118-2127.

Carulla, N.; Woodward, C.; Barany, G.; "Synthesis and characterization of a b-hairpin peptide that represents a 'core module' of bovine pancreatic trypsin inhibitor (BPTI)", (2000) Biochemistry, 39(27), 7927-7937.

Wang, M.; McIntee, E.J.; Cheng, G.; Shi, Y.; Villalta, P.; Hecht, S.S.; "Identification of Paraldol-Deoxyguanosine Adducts in DNA Reacted with Crotonaldehyde", (2000) Chem. Res. Toxicol., 13, 1065-1074.

Hogenkamp, H.P.C.; Collins, D.A.; Live, D.; Benson, L.M.; Naylor, S.; "Synthesis and Characterization of nido-Carborane-Colbalamin Conjugates", (2000) Nuclear Medicine & Biology, 27, 89-92.

Paterlini, M.G.; Avitable, F.; Ostrowski, B.G.; Ferguson, D.M.; Portoghese, P.S.; "Stereochemical requirements for receptor recognition of the opiod peptide endomorphin-1", (2000), Biophysical Journal, 78, 590-599.

Zangger, K.; Oz, G.; Armitage, I.M.; "Re-evaluation of the Binding of ATP to Metallothionein", (2000)J. Biol. Chem., 275, 7534-7538.

Beuning, P.J.; Tessmer, M.R.; Baumann, C.G.; Kallick, D.A.; Musier-Forsyth, K.; "Sequence Dependent Conformational Differences of Small RNAs Revealed by Native Gel Electrophoresis", Analytical Biochemistry, 273, 284-290 (1999).

Chang, S.-L.; Waller, B.J.; Lipscomb, J.D.; Mayo, K.H.; "Solution Structure of Component B from Methan Monooxygenase Derived Through Heteronuclear NMR and Molecular Modeling", Biochemistry, 38, 5799-5812 (1999).

Daragan, V.A.; Mayo, K.H.; "Using the Model Free Approach to Analyze NMR Relaxation Data in Cases of Anisotropic Molecular Diffusion", J. Phys. Chem., 103, 6829-6834 (1999).

Griffioen, A.; Damen, C.; Marinotti, S.; Blijham, G.; Groenewegen, G.; Mayo, K.H.; "Angiogenesis Inhibitors Overcome Tumor-Induced Endothelial Cell Anergy", Int. J. Cancer, 80, 315-319 (1999).

Hwang, T.-L.; van Zijl, P.C.M.; Garwood, M.; "Asymmetric adiabatic pulses for NH selection", Journal of Magnetic Resonance, 138, 173-177 (1999).

Klaus, W.; Labhardt, A.; Buchwald, P.; Hunziker, W.; Kallick, D.A.; "Secondary structural elements of calbindinD28 I,II as determined by multinuclear and multidimensional NMR", European Journal of Biochemistry, 262, 933-938 (1999).

Live, D.H.; Williams, L.J.; Kuduk, S.D.; Schwarz, J.B.; Glunz, P.W.; Chen, X.-T.; Sames, D.; Kumar, R.A.; Danishefsky, S.J.; "Probing cell-surface architecture through synthesis: An NMR-determined structural motif for tumor-associated mucins", Proceedings of the National Academy of Science, 96, 3489-3493(1999).

Mikhailov, D.V.; Young, H.; Lindhardt, R.J.; Mayo, K.H.; "Heparin Dodecasaccharide Binding to Platelet Factor-4 and Growth-related Protein-alpha: Induction of a Partially Folded State and Implications for Heparin-Induced Thromnocytopenia", J.Biol. Chem., 274, 25317-25329 (1999).

Mikhailov, D.V.; Washington, L.; Voloshin, A.M.; Daragan, V.A.; Mayo, K.H.; "Angular Variances for Internal Bond Rotations of Side-Chains in GXG-Based Tripeptides derived from 13C-NMR Relaxation Measurements", Biopolymers, 49, 373-383 (1999).

Okar, D.A.; Live, D.H.; Kirby, T.L.; Karschinia, E.J.; von Weymarn, L.B.; Armitage, I.M.; Lange, A.J.; "Mutational Analyses of the histidine residues in the bisphosphatase domain of the rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by NMR spectroscopy reveal that Glu-327 and His-446 participate in a network of hydrogen bonds that includes the catalytic site", Biochemistry, 38, 4471-4479, (1999).

Young, H.; Roongta, V.; Daly, T.J.; Mayo, K.H.; "NMR Structure and Dynamics of Monomeric Neutrophil Activating Peptide-2", Biochem. J., 338, 591-598 (1999).

Yu, Y.-C.; Roongta, V.; Daragan, V.A.; Mayo, K.H.; Tirrell, M.; Fields, G.B.; "Structure and Dynamics of Peptide-Amphiphiles Incorporating Triple-Helical Proteinlike Molecular Architecture", Biochemistry, 38, 1659-1668 (1999).

Zangger, K.; Oz, G.; Otvos, J.D.; Armitage, I.M.; "Three-dimensional solution structure of mouse [Cd7]-metallothionein-1 by homonuclear and heteronuclear NMR spectroscopy", Protein Science, 8, 2630-2638 (1999).

Daragan, V.A.; Mayo, K.H.; "A Simple Approach to Analyzing Protein Side-Chain Dynamics from 13C Relaxation Data", J.Magnetic Resonance, 130, 329-334 (1998).

Griffioen, A.; Barendsz-Janson, A.F.; Mayo, K.H.; Hillen, H.F.P.; "Angiogenesis, a Target for Tumor Therapy", J. Lab. Clin. Med., 132, 363-368 (1998).

Mayo, K.H.; Haseman, J.; Ilyina, E.; Gray, B.H.; "Designed Beta-Sheet-forming Peptide 33mers with Potent B/PI-like Bactericidal and Endotoxin Neutralizing Activities", Biochim. Biophys. Acta, 1425, 81-92 (1998).

Mayo, K.H.; Ilyina, E.; "A Folding Pathway for Betapep-4 Peptide 33mer: From Unfolded Monomers and Beta-sheet Sandwich Dimers to Well-Structured Tetramers", Protein Science, 7, 358-368 (1998).

Ramirez, M.; Daragan, V.A.; Serrano, L.; Mayo, K.H.; "Motional Dynamics of Residues in a Beta-Hairpin Peptide Measured by 13C-NMR Relaxation", Protein Science, 7, 720-729 (1998).

Zangger, K.; Armitage, I.M.; "Sensitivity-enhanced detection of fast exchanging protons by an exchange-edited gradient HEHAHA-HSQC experiment", Journal of Magnetic Resonance, 135, 70-75 (1998).

Daragan, V.A.; Mayo, K.H.; "Motional Model Analyses in Proteins and Peptides using 13C and 15N NMR Relaxation", Progress in NMR Spectroscopy, 31, 63-105 (1997).

Daragan, V.A.; Ilyina, E.; Fields, C.G.; Fields, G.B.; Mayo, K.H.; "Backbone and side-chain dynamics of residues in a partially folded Beta-sheet peptide from PF4", Protein Science, 6, 355-363 (1997).

Ilyina, E.; Roongta, V.; Pan, H.; Woodward, C.; Mayo, K.H.; "A Pulsed-Field Gradient NMR Study of Bovine Pancreatic Trypsin Inhibitor Self-Association", Biochemistry, 36, 3383-3388 (1997).

Ilyina, E.; Roongta, V.; Mayo, K.H.; "NMR Structure of a de Novo Designed Peptide 33mer with Two Distinct, Compact Beta-Sheet Folds", Biochemistry, 36, 5245-5250 (1997).

Ilyina, E.; Roongta, V., Mayo, K.H.; "Designing Water Soluble Beta-Sheet Peptides with Compact Structure", Techniques in Protein Chemistry VIII, 797-808 (1997).

Mayo, K.H.; Fields, G.B.; "Peptides as Models for Understanding Protein Folding", Advances in Molecular and Cell Biology, 22, 565-611 (1997).

Mayo, K.H., "Solution NMR Characterization of Peptide Folding", Methods in Enzymology, 289, 646-672 (1997).

Mayo, K.H., "NMR and X-Ray Studies of Collagen Model Peptides", Biopolymers, 40, 359-370 (1997).

McCornack, M.A.; Kakalis, L.T.; Caserta, C.; Handschumacher, R.E.; Armitage, I.M.; "HIV protease substrate conformation: modulation by cyclophilin A", FEBS Letters, 414, 84-88(1997).

Mikhailov, D.; Linhardt, R.J.; Mayo, K.H.; "NMR Solution Conformation of Heparin-derived Hexasaccharide", Biochemical Journal, 328, 51-61 (1997).

Tessmer, M.R.; Kallick, D.A.; "Role of Tryptophan 14 in Dynorphin A(1-17) in its Interaction with a Model Membrane", International Journal of Peptide and Protein Research, J. Peptide Res., 49, 427-431 (1997).

Tessmer, M.R.; Kallick, D.A.; "NMR and Structural Model of Dynorphin A(1-17) in a Model Membrane", Biochemistry, 36, 1971-1981 (1997).

Tessmer, M.R.; Meyer, J.P.; Hruby, V.; Kallick, D.A.; "Solution Structure of a Potent Cyclic Dynorphin Analog Bound to Micelles", Journal of Medicinal Chemistry, 40, 2148-2155 (1997).

Tessmer, M.R.; Meyer, J.P.; Hruby, V.; Kallick, D.A.; "Solution Structure of a Potent Cyclic Dynorphin Analog Bound to Micelles", Journal of Medicinal Chemistry, 40, 2148-2155 (1997).

Uknis, M.R.; Wasiluk, K.R.; Acton, R.D.; Klaerner, H.G.; Dahlberg, P.S.; Ilyina, E.; Haseman, J.; Gray, B.H.; Mayo, K.H.; Dunn, D.L.; "Design of a Potent Novel Endotoxin Antagonist", Surgery, 122, 380-385 (1997).

Avdulov, N.A.; Chochina, S.V.; Daragan, V.A.; Schroeder, F.; Mayo, K.H.; Wood, W.G.; "Direct Binding of Ethanol to bovine serum albumin: A fluorescent and 13C-NMR Multiplet Relaxation Study", Biochemistry, 35, 340-347 (1996).

Daragan, V.A.; Mayo, K.H.; "Analysis of internally restricted correlated rotations in peptides and proteins using 13C- and 15N-NMR relaxation data", J. Phys. Chem., 100, 8378-8388 (1996).

Daragan, V.A.; Mayo, K.H.; "Analysis of internally restricted correlated rotations in peptides and proteins using 13C- and 15N-NMR relaxation data", J. Phys. Chem., 100, 8378-8388 (1996).

Daragan, V.A.; Mayo, K.H.; "A novel model-free analysis of 13C NMR relaxation of alanine methyl side-chain motions in peptides", J. Mag. Reson., 110, 164-175 (1996).

Mayo, K.; Ilyina, E.; Park, H.; "A Recipe for Designing Water Soluble Beta-Sheet-forming Peptides", Protein Sci., 5, 1301-1315 (1996).

Mayo, K.H.; Fan, F.; Beavers, M.; Eckardt, A.; Keane, P.; Hoekstra, W.; Andrade-Gordon, P., "Integrin Receptor GPIIb/IIIa Bound State Conformation of the Fibrinogen Gamma-Chain C-Terminal Peptide 400-411: NMR and Transfer NOE Studies", Biochemistry, 35, 4434-4444 (1996).

Mayo, K.H.; Fan, F.; Beavers, M.; Eckardt, A.; Kean, P.; Hoekstra, W.; Andrade-Gordon, P.; "RGD induces conformational transition in purified platelet integrin GPIIb/IIIa-SDS system yielding multiple binding states for fibrinogen gamma-chain C-terminal peptide", FEBS Letts, 378, 79-82 (1996).

Mayo, K.H.; an, F.; Beavers, M.; Eckardt, A.; Keane, P.; Hoekstra, W.; Andrade-Gordon, P.; "NOE-derived conformation of GRGDSP cell adhesion recognition site in the presence of SDS micelles and integrin receptor GPIIb/IIIa", Biochim.Biphys. Acta, 1296, 95-102 (1996).

Mikhailov, D.; Mayo, K.H.; Pervin, A.; Linhardt, R.J.; "13C-NMR Relaxation Study of Heparin-Disaccharide Interactions with Tripeptides GRG and GKG", Biochem. J., 315, 447-454 (1996).

Mikhailov, D.; Mayo, K.; Vlahov, I.R.; Toida, T.; Pervin, A.; Lindhardt, R.J.; "NMR Solution Conformation of Heparin-derived Tetrasaccharide", Biochem. J. 318, 93-102 (1996).

Varnum, J.M.; Thakur, M.; Mayo, K.H.; Jansen, S.A.; "Stability and Conformational Analysis of Tc-RC160 and Re-RC160: Experimental and Theoretical Analysis of the Influence of Metal Complexation on the Structural Requisites for Activity", J.Phys.Chem., 100, 14630-14636 (1996).

Yao, L.J.; Mayo, K.H.; "Interactions of integrin GPIIb/IIIa-derived peptides with fibrinogen investigated by NMR spectroscopy", Biochem. J., 315, 161-170 (1996).

Barker, S.; Mayo, K.; "Quarternary Structure Amplification of Protein Folding Differences Observed in 'Native' Platelet Factor-4", FEBS Letts, 357, 301-304 (1995).

Battafarano, R.J.; Dahlberg, P.S.; Ratz, C.A.; Johnston, J.W.; Gray, B.H.; Haserman, B.S.; Mayo, K.H.; Dunn, D.L.; "Peptide derivatives of three distinct lipolysaccharide binding proteins inhibit lipopolysaccharide-induced tumor necrosis factor-alpha Secretion in vitro", Surgery, 118, 318-324 (1995).

Daragan, V.; Mayo, K.; "Using the model free approach to interpret 13C NMR multiplet relaxation data from peptides and proteins", J. Magn. Reson., 107, 274-278 (1995).

Fan, F.; Mayo, K.H.; "Effect of pH on the Conformation and Backbone Dynamics of a 27 Residue Peptide in Trifluoroethanol: An NMR and CD Study", J.Biol.Chem., 270, 24693-24701 (1995).

Gray, B.; Haseman, J.; Mayo, K.; "B/PI-derived Synethetic Peptides: Synergistic Effects in Tethered Bactericidal and Endotoxin Neutralizing Peptides", B.B.A. 1244, 185-190 (1995).

Hoekstra, W.; Bonner, M.P.; Andrade-Gordon, P.; Mayo, K.; Fan, F.; Keane, P.; Durkin, K.; Liotta, D.C.; Kloczewiak, M.; Tomko, K.; Evangelisto, M.F.; Press, J.B.; "Design and Evaluation of Nonpeptide Fibrinogen Gamma Chain Based GPIIB/IIIA Antagonists", J.Med.Chem., 38, 1582-1592 (1995).

Ilyina, E.; Mayo, K.; "Multiple Native-like Conformations Trapped via Self-Association-Induced Hydrophobic Collapse of the 33 Residue Beta-Sheet Domain from Platelet Factor-4", Biochem. J., 306, 407-419 (1995).

Kaboyanski, E.B.; Zhu, C.; Kallick, D.A.; Roth, D.B.; "Hairpin opening by single-strand nucleases", Nucleic Acids Research, 23, 3872-3881 (1995).

Kallick, D.A.; Tessmer, M.R.; Watts, C.R.; Li, C.-Y.; "The Use of Dodecylphosphocholine Micelles in Solution NMR", Journal of Magnetic Resonance, Series B, 109, 60-65 (1995).

Mayo, K.H.; Roongta, V.; Barker, S.; Milius, R.; Ilyina, E.; Quinlan, C.; La Rosa, G.; Daly, T.; "NMR Solution Structure of the 32 kD Tetrameric Platelet Factor-4 ELR-Motif N-terminal Chimer: A Symmetric Tetramer", Biochemistry, 34, 11399-11409 (1995).

Mayo, K.H.; Ilyina, E.; Roongta, V.; Dundas, M.; Joseph, J.; Lai, C.K.; Maione, T.; Daly, T.; "Heparin Binding to Platelet Factor-4. An NMR and Site-Directed Mutagenesis Study: Arginine Residues Crucial for Binding", Biochemical Journal, 312, 357-365 (1995).

Mkhailov, D.; Daragan, V.; Mayo, K.; "13C-Multiplet NMR Relaxation-Derived Ring Puckering and Backbone Dynamics in Proline-Containing Glycine-Based Peptides", Biophyics J., 68, 1540-1550 (1995).

Mikhailhov, D.; Daragan, V.; Mayo, K.; "Lysine Side-Chain Dynamics Derived from 13C Multiplet NMR Relaxation Studies on Di- and Tri-Peptides", J.Biomol.NMR, 5, 397-410 (1995).

Watts, C.R.; Tessmer, M.R.; Kallick, D.A.; "Structure of Leu5-enkephalin bound to a model membrane as determined by high resolution NMR", Letters in Peptide Science, 2, 59-70 (1995).

Watts, C.R.; Kervin, S.; Kuntz, I.D.; Kenyon, G.; Kallick, D.A.; "Rationally designed N, N'-bis[(N-p-guanidinobenzyl-N-methyl)aminocarbonyl] 1,3-diaminobenzene, 'BIGBEN', binds to the minor groove of d(CGCGAATTCGCG)2 as determined by two-dimensional nuclear magnetic resonance spectroscopy', Journal of the American Chemical Society, 117, 9941-9950(1995).

Kallick, D.A., "The Conformation of Dynorphin A(1-17) Bound to Dodecylphosphocholine Micelles", Journal of the American Chemical Society, 115 9317-9318 (1993).

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