Nuclear Magnetic Resonance Facility

The Structural Biology NMR Resource is a user facility whose goal is to make state-of-the-art NMR instruments available to researchers, providing a venue for them to pursue their projects and develop their experience in NMR methods.

The facility is a resource of the University of Minnesota Medical School under the Department of Biochemistry Microbiology and Biophysics (BMBB).  The facility is housed in Nils Hasselmo Hall. 

The facility is home to seven superconducting magnets.  Available liquid-state instruments include four Varian Inova NMR spectrometers at field strengths of 800 MHz (equipped with Cold Probe), 600 MHz (2) and 500 MHz with triple-axis gradients, and a Bruker Avance 700 MHz NMR spectrometer with CryoProbe^TM and sample changer.  Also available are two high field Varian solid-state NMR spectrometers (600 MHz and 700 MHz).  The instruments are equipped with a full range of probes.

In addition to the instruments above, the facility partners with the Center for Drug Design, Department of Medicinal Chemistry and Institute of Therapeutic Discovery and Development to provide maintenance and expertise for NMR instruments located in their laboratories.

Top priorities of the facility personnel are to maintain the performance of these instruments at the highest level and to provide basic training to new users.  In addition, the resident expertise is available to facilitate NMR efforts and contribute to the scientific research efforts of users in the development of strategies for data collection and analysis.